TY  - JOUR
T1  - Comparison of Bacterial Cellulose and Acellular Dermal Matrices Seeded with Fibroblasts versus Free Gingival Grafts: A Randomized Animal Study
A1  - Giulia Romano
A1  - Marco Bianchi
A1  - Paolo Conti
JF  - Journal of Orthodontic and Periodontal Biomaterials Research
Y1  - 2024
VL  - 4
IS  - 2
SP  - 124
EP  - 134
N2  - Mucogingival defects (MGDs), such as dental root recessions, decreased vestibular depth, and absence of keratinized tissues, are commonly seen in dental clinics. MGDs may result in functional, aesthetic, and hygienic concerns. In these situations, autogenous soft tissue grafts are considered the gold-standard treatment. This study compares the healing process of free gingival grafts (FGGs) to bacterial cellulose matrix (BCM) and human acellular dermal matrix (ADM) seeded with fibroblasts from culture supplemented with platelet-rich plasma in a rat model. Surgical defects were made in rats, which received the following treatments in a randomized manner: group I, negative control (defect creation only); group II, positive control (FGG); group III, BCM; group IV, BCM + fibroblasts; group V, ADM; and group VI, ADM + fibroblasts. Clinical, histological, and immunological analyses were performed 15 days after grafting. Clinical examinations recorded epithelium regularity and the presence of ulcers, erythema, and/or edema. The histological analysis revealed the degree of reepithelization, width, regularity, and presence of keratin. The Fisher exact statistical test was applied to the results (P
UR  - https://galaxypub.co/article/comparison-of-bacterial-cellulose-and-acellular-dermal-matrices-seeded-with-fibroblasts-versus-free-ifr6bo1aybnarmm
ER  -