TY  - JOUR
T1  - Drug-Based Strategies for Weight Reduction and Their Interaction with the Human Gut Microbiota
A1  - Victoria Lee
A1  - Ethan Kim
A1  - Jasmine Singh
JF  - Annals of Pharmacy Practice and Pharmacotherapy
JO  - Ann Pharm Pract Pharmacother
SN  - 3062-4436
Y1  - 2025
VL  - 5
IS  - 1
DO  - 10.51847/OobVHFcZjv
SP  - 194
EP  - 200
N2  - At the onset of the twenty-first century, obesity has emerged as a major global health concern due to its widespread prevalence in modern populations. It is a metabolic disorder characterized by excessive accumulation of adipose tissue, primarily driven by increased caloric intake, reduced energy expenditure, and dysregulation of hunger signals. Obesity is a chronic systemic condition that contributes to numerous health complications, with the most common being type 2 diabetes mellitus, arterial hypertension, atherosclerosis, sleep apnea, various forms of cancer, and more.

Over the past decade, considerable progress has been made in the pharmacological management of endocrine and metabolic disorders, and several of these new therapies have demonstrated efficacy in treating obesity. Growing evidence suggests that such medications may influence the human gut microbiota—a complex community of commensal bacteria residing in the gastrointestinal tract—which can impact appetite regulation, mucosal integrity, and nutrient absorption. Understanding this interaction may be pivotal for elucidating the mechanisms underlying obesity and optimizing its treatment.
UR  - https://galaxypub.co/article/drug-based-strategies-for-weight-reduction-and-their-interaction-with-the-human-gut-microbiota-hc40qiveorjyjrx
ER  -