TY  - JOUR
T1  - Exploring the Wound Healing Potential of Aqueous Extracts from Caucasus Herbs in Diabetes Mellitus
A1  - Alexandra Sergeevna Tsiganock
A1  - Anastasiia Evgenevna Bgantseva
A1  - Viktoria Romanovna Vostrikova
A1  - Daniil Sergeevich Shevel
A1  - Azman Ilesovna Saidarova
A1  - Ilishan Magamedovich Bekbuzarov
A1  - Tagir Kurbanovich Kurbanov
A1  - Saida Muradinovna Shadova
JF  - Specialty journal of Pharmacognosy, Phytochemistry, and Biotechnology
JO  - Spec J Pharmacogn Phytochem Biotechnol
SN  - 3062-441X
Y1  - 2023
VL  - 3
IS  - 1
DO  - 10.51847/Y5Fvcyw12s
SP  - 31
EP  - 38
N2  - Diabetes mellitus is a common condition that often leads to serious systemic complications. This study investigates the healing of infected wounds in hyperglycemia using formulations derived from plant materials such as Acacia nilotica, Trigonella foenumgraecum, Cyperus rotundus, and Cymbopogon proximus. A model of dexamethasone-induced hyperglycemia was created, followed by wound induction and the application of Streptococcus epidermidis-infected material from a patient with streptoderma. The findings indicate that aqueous emulsions containing these plant extracts positively affected the dysmetabolic changes associated with dexamethasone-induced hyperglycemia, such as decreased hepatic transaminase activity and normalized blood glucose levels. In addition, the composition of peripheral blood improved with increases in erythrocytes and hemoglobin and a reduction in leukopenia. These changes provide a supportive environment for wound healing, overcoming the inhibitory effects of dexamethasone-induced injury on regenerative processes.
UR  - https://galaxypub.co/article/exploring-the-wound-healing-potential-of-aqueous-extracts-from-caucasus-herbs-in-diabetes-mellitus-sw3xbnyqetgzshi
ER  -