TY  - JOUR
T1  - From Latent System Conditions to Patient Injury: How Medication-Process Deviations Become Harm and Where Recovery Remains Possible
A1  - Mei Lin
A1  - David Thompson
A1  - Nadia Haddad
JF  - Annals of Pharmacy Practice and Pharmacotherapy
JO  - Ann Pharm Pract Pharmacother
SN  - 3062-4436
Y1  - 2023
VL  - 3
IS  - 2
DO  - 10.51847/0ENPu55Ovu
SP  - 42
EP  - 50
N2  - Medication-process deviations are frequently treated as interchangeable indicators of medication harm, although many never alter drug exposure and many exposure changes are detected or corrected before injury occurs. The clinically important question is therefore not simply whether an error occurred, but how a deviation interacts with the work system, the resulting exposure, patient susceptibility, detection timing, and remaining opportunities for recovery. This Current Opinion separates process failure from harm realization across prescribing, dispensing, administration, monitoring, communication, and subsequent patient response. It argues that latent conditions configure which deviations arise and whether they propagate; altered or omitted medication exposure provides a critical link between process failure and clinical consequence; and recovery remains possible only while a deviation is detectable and its consequences remain reversible or mitigable. Human-factors adaptations and technologies can both strengthen and weaken safety depending on how they alter workload, information flow, attention, and coordination. The proposed synthesis therefore treats medication harm as a conditional trajectory rather than the inevitable endpoint of a process deviation. This distinction has implications for measurement, intervention evaluation, safety-system design, and attribution of medication-related injury.
UR  - https://galaxypub.co/article/from-latent-system-conditions-to-patient-injury-how-medication-process-deviations-become-harm-and-w-qdnuyrzmwh1zixz
ER  -