TY  - JOUR
T1  - Outcomes of Initial Therapy in Patients with Ovarian, Fallopian Tube, or Peritoneal Cancer: Insights from a German Clinical Cancer Registry Analysis
A1  - N. Abdel-Rahman
A1  - M. El-Sayed
A1  - T. Fawzy
JF  - Asian Journal of Current Research in Clinical Cancer
JO  - Asian J Curr Res Clin Cancer
SN  - 3062-4444
Y1  - 2021
VL  - 1
IS  - 2
DO  - 10.51847/IJDQjRteJ4
SP  - 32
EP  - 40
N2  - Current ovarian cancer (OC) treatment follows the “Three-Pillar-Model,” which includes surgery, chemotherapy, and maintenance therapy. This study presents the first comprehensive analysis of a federal cancer registry for OC patients from Berlin and Brandenburg in Germany. The main aim was to assess established quality indicators, including surgical outcomes, use of adjuvant chemotherapy, and completeness of surgical staging in early-stage disease. Data from the Clinical Cancer Registry of Brandenburg and Berlin covering 2009–2019 were examined. Study objectives were defined by a panel of specialized physicians. Analyses included descriptive statistics and survival evaluations. A total of 2,771 primary OC cases were evaluated. Histological subtypes largely aligned with expectations, with high-grade serous OC predominating in advanced stages. Complete surgical staging was achieved in 57% of FIGO I–IIA cases, while macroscopic complete resection was accomplished in 53% of patients with FIGO stage >III. Five-year survival rates ranged from 79% for FIGO I to 40% for FIGO III. The proportion of patients receiving adjuvant chemotherapy exceeded 50%. These findings provide insight into quality metrics and treatment outcomes, demonstrating generally favorable results for patients with primary OC. Nevertheless, observed gaps highlight areas for improvement and can inform the development of new quality indicators to enhance patient care.
UR  - https://galaxypub.co/article/outcomes-of-initial-therapy-in-patients-with-ovarian-fallopian-tube-or-peritoneal-cancer-insights-e6vim7a9rwmrmge
ER  -