%0 Journal Article
%T Pharmacogenetic Insights into Glucagon-Like Peptide-1 Receptor and Its Role in Diabetes Therapy
%A Chloe Davis
%A Liam Taylor
%A Isabella Moore
%J Annals of Pharmacy Practice and Pharmacotherapy
%@ 3062-4436
%D 2023
%V 3
%N 1
%R 10.51847/QbAABZN70k
%P 145-154
%X Type 2 diabetes mellitus (T2DM) represents a multifactorial metabolic disorder primarily marked by impaired insulin secretion and the presence of insulin resistance. If left untreated, T2DM inevitably progresses to various long-term complications. The emergence of novel therapeutic agents, such as Glucagon-like Peptide-1 receptor agonists (GLP-1 RAs), has introduced new possibilities for improved glycemic regulation and additional metabolic advantages. Pharmacogenetics, a branch of pharmacotherapy, explores how genetic polymorphisms influence individual responses to specific medications. This review focuses on the current scientific understanding of the pharmacogenetics of GLP-1 receptor agonists—particularly liraglutide—and their potential role in the personalized management of T2DM.
%U https://galaxypub.co/article/pharmacogenetic-insights-into-glucagon-like-peptide-1-receptor-and-its-role-in-diabetes-therapy-7ml68zfy3zoxorq