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Interdisciplinary Research in Medical Sciences Specialty

2021 Volume 1 Issue 1
Creative Commons License

Comparative Analysis of Two Vector Systems in mRNA Vaccine Development


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  1. Department of Biomedical Sciences, University of Applied Sciences, Bonn-Rhein-Sieg, Bonn, Germany.
  2. Department of Medical Laboratory Management, Federal School of Medical Laboratory Science, Jos, Nigeria
Abstract

The present study aimed to produce an mRNA vaccine and analyze two types of vectors. According to this study, the Food and Drug Administration has fully approved the mRNA vaccine as the most effective vaccine against the 2019 coronavirus sickness. The lack of anti-vector immunity, the infrequent occurrence of insertional mutagenesis associated with it, and its therapeutic efficacy all contribute to this approval. In addition, it has an edge over traditional DNA vaccines due to its quick production method. A review was conducted based on the available online literature. The procedures used to generate mRNA vaccine in vitro are described in detail in this review. A plasmid containing the super folder green fluorescent protein and the receptor-binding domain present in the coronavirus spike protein is used as an example. A notice for further information on the use of a viral vector in the production of these vaccines is also included.


How to cite this article
Vancouver
Ohanube GAK, Obeta UM. Comparative Analysis of Two Vector Systems in mRNA Vaccine Development. Interdiscip Res Med Sci Spec. 2021;1(1):1-10.
APA
Ohanube, G. A. K., & Obeta, U. M. (2021). Comparative Analysis of Two Vector Systems in mRNA Vaccine Development. Interdisciplinary Research in Medical Sciences Specialty, 1(1), 1-10.

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