Contemporary Pharmacological Studies and Therapeutic Uses of the Medicinal Insect Coridius chinensis

Coridius chinensis, a traditional medicinal insect in China, consists of the dried whole insect from the Pentatomidae family (Coridius chinensis Dallas). Recent pharmacological research has isolated and characterized over 100 bioactive small molecules from this species. Experimental studies have revealed multiple pharmacological effects, including pain relief, antioxidant activity, anticancer potential, anticoagulation, and antibacterial properties. Traditionally, it has been used in Chinese medicine formulations to manage conditions such as impotence, hemangioma, and various types of pain. Despite these findings, comprehensive understanding of its pharmacological mechanisms remains limited. This review compiles current domestic and international research on Coridius chinensis, highlighting its key chemical constituents, biological activities, and therapeutic applications, offering a foundation for future development and utilization of this insect in traditional medicine.