Formulation and Evaluation of Immediate-Release Quetiapine Fumarate Tablets

Antipsychotic medications can help manage the symptoms of schizophrenia. Several demographic and scientific elements have the potential to influence the choice of unusual neuroleptic drugs. Bipolar disorder and schizophrenia can be treated with quetiapine fumarate. When making tablets and hard-shell capsules, disintegrating agents are often utilized ingredients. The primary goal of this study was to develop a dependable immediate-release tablet formulation of the antipsychotic quetiapine. Tablets' enhanced stability and simulated tamper resistance, along with their lower cost, packaging, and delivery, make them popular. Faster-dissolving oral tablets have a higher bioavailability and shorter absorption time. Drugs should dissolve or disintegrate in the stomach shortly after absorption. The most common breakdown agent used in tablet manufacturing is starch. Along with developing a pharmaceutically equivalent instantaneous-release tablet for people with mental illnesses such as bipolar disorder and schizophrenia, this initiative aims to develop a chemically and physically stable generic formulation for the treatment of schizophrenia.