The term “Constitution of Traditional Chinese Medicine” refers to the physical and psychological characteristics of the body remaining constant. Unbalanced TCMCs make people more susceptible to illness. To evaluate the effectiveness of TCMCs, this study examined how Chinese healthy women and breast cancer patients were disseminated in Hong Kong. To analyze the physical constitution scale in TCM and identify the TCMC categories, 305 healthy women and 305 BC women were recruited for the study. Questionnaires were used to prepare the sociodemographic information and related BC risk factors. Multiple-factor analysis was used to identify the relationship between BC and imbalanced TCMC forms. Compared to healthy individuals, BC patients had a significantly higher percentage of unbalanced TCMC, in particular, qi-depressed, Yin-deficiency, blood stasis, qi-deficiency, and wetness-heat (P < 0.05). According to the results of the stepwise logistic regression analysis, there was a positive correlation between qi-depressed and BC (CI = 1.49-6.92; OR = 3.21). The link significantly increased when qi-depressed constitutions were combined with wetness-heat (CI = 1.83-12.71; OR = 4.82) or blood-stasis (CI = 1.31-8.16; OR = 3.27). BC was associated with both constitutions (CI = 1.02-8.17; OR = 2.88). The qi-depressed's constitution was a risk factor for BC on its own. Similarly, when combined with qi-depressed, the constitutions of the blood-stasis and wetness-heat may also play important roles in the incidence of BC. This result raises the prospect that individuals with BC vulnerabilities may exhibit inconsistent unbalanced TCMC types, suggesting that Chinese constitutional analysis could be a viable method for identifying BC-vulnerable populations and the consequent inhibition of BC.