Poor asthma outcomes are frequently linked to incorrect inhaler use and limited patient understanding. While community pharmacists play a crucial role in patient education, relying solely on verbal explanations may not be efficient in busy pharmacy environments. Artificial intelligence (AI)–based tools offer an engaging and tailored method for delivering asthma self-management support. This study explored how pharmacist-facilitated AI education influences patients’ inhaler skills and asthma comprehension in Jordan. A pre–post interventional design was used in five community pharmacies located in southern Jordan. Adult asthma patients (≥18 years) who were prescribed metered-dose or dry-powder inhalers attended 20–30 minute pharmacist-led sessions combining traditional instruction with AI-powered interactive demonstrations. Outcomes included asthma knowledge (evaluated by a 10-question test) and inhaler performance (assessed using a 10-step checklist) at baseline and one week after the educational session. The study enrolled 400 participants (59% female; mean age 42.3 ± 14.8 years). Correct inhaler use increased substantially from 42% before the intervention to 89% afterward (difference 47%; 95% CI: 41–53; p < 0.001). Knowledge scores improved significantly from 4.3 ± 1.2 to 8.5 ± 1.0 (mean change +4.2; 95% CI: 4.0–4.4; p < 0.001). The largest improvements were seen among female participants and those with university-level education. A strong positive association was found between knowledge and inhaler performance (r = 0.71). Integrating AI-based learning with pharmacist guidance led to significant advancements in both asthma knowledge and inhaler handling. This practical and scalable approach may enhance patient care within community pharmacies and contribute to international efforts aimed at improving asthma management and self-care practices.
