We'd appreciate your feedback. Send feedback Subscribe to our newsletters and alerts


Asian Journal of Current Research in Clinical Cancer

2024 Volume 4 Issue 1

Pulmonary Carcinosarcoma: A Rare and Poor Prognosis Cancer–A Retrospective Analysis


  1. Department of Internal Medicine, Faculty of Medicine, Jazan University, Jazan, Saudi Arabia.
  2. Department of Pulmonary Medicine, Amsterdam University Medical Center, Amsterdam, Netherlands.
Abstract

Pulmonary carcinosarcoma (PCS) is an uncommon and aggressive cancer, characterized by a combination of epithelial and sarcomatous tissue components. It is responsible for less than 1% of all lung tumors and usually affects older male smokers. However, the clinicopathological features and biological behavior of PCS remain insufficiently explored. This study aimed to shed light on these aspects. A total of eight patients with pathologically confirmed PCS were included in this retrospective study. The tumors varied in size, with diameters ranging from 3.5 cm to 21.5 cm. Six patients had central tumors, while the remaining two had peripheral lesions. Symptoms were largely dependent on the location of the tumor and included coughing, shortness of breath, and hemoptysis. Surgical resection was performed in seven patients, although PCS is known for its rapid progression and frequent metastasis, which results in a poor prognosis and limited survival, usually between 6 months and 1 year. The role of neoadjuvant and adjuvant chemotherapy-radiotherapy remains controversial, and there is no consensus on its effectiveness. Surgical resection of the lung is still considered the most appropriate treatment, but even with this intervention, survival rates are generally low. Given the rarity and challenging nature of PCS, further studies are needed to explore more effective treatment options for this cancer.


How to cite this article
Vancouver
Hakami A. Pulmonary Carcinosarcoma: A Rare and Poor Prognosis Cancer–A Retrospective Analysis. Asian J Curr Res Clin Cancer. 2024;4(1):31-9. https://doi.org/10.51847/ANsF5Aosvo
APA
Hakami, A. (2024). Pulmonary Carcinosarcoma: A Rare and Poor Prognosis Cancer–A Retrospective Analysis. Asian Journal of Current Research in Clinical Cancer, 4(1), 31-39. https://doi.org/10.51847/ANsF5Aosvo
Articles
Tolerability of Chemoradiotherapy in Geriatric Patients with Pancreatic Cancer
Asian Journal of Current Research in Clinical Cancer
Vol 5 Issue 1, 2025 | İrem Sarıcanbaz
Environmental Impact of the Y-Isomer of HCH: Unveiling Its Role in Cancer Formation
Asian Journal of Current Research in Clinical Cancer
Vol 2 Issue 2, 2022 | Mata Uvaysovna Razhaeva
An Overview of Targeted Therapy Applications in Cancer Treatment
Asian Journal of Current Research in Clinical Cancer
Vol 5 Issue 1, 2025 | Yeuan Ting Lee
Exploring Advanced Diagnostic Techniques for Salivary Gland Disorders: A Narrative Overview
Asian Journal of Current Research in Clinical Cancer
Vol 4 Issue 1, 2024 | Chuan Xiang Li
Alternative Perspective on Cancer Based on the Interaction between Plasma Radiation and DNA
Asian Journal of Current Research in Clinical Cancer
Vol 2 Issue 1, 2022 | Mahmoud Mohamed Ahmed
Theoretical Model of Thiophene and Its Derivatives Interaction with BRCA-1
Asian Journal of Current Research in Clinical Cancer
Vol 4 Issue 2, 2024 | Lauro FigueroaValverde
Tolerability of Chemoradiotherapy in Geriatric Patients with Pancreatic Cancer
Asian Journal of Current Research in Clinical Cancer
Vol 5 Issue 1, 2025 | İrem Sarıcanbaz
An Overview of Targeted Therapy Applications in Cancer Treatment
Asian Journal of Current Research in Clinical Cancer
Vol 5 Issue 1, 2025 | Yeuan Ting Lee
Evaluating the Effects of Plasma Irradiation and Stevia on Gene Expression and Immune Responses in HepG2 Cells
Asian Journal of Current Research in Clinical Cancer
Vol 5 Issue 1, 2025 | Fatma Hussein Abdelwahab
Long-Term Survival Outcomes of Colorectal Cancer Survivors: An In-Depth Exploration
Asian Journal of Current Research in Clinical Cancer
Vol 5 Issue 1, 2025 | Zhaobei Cai
Superficial Basal Cell Carcinoma of the Nipple Mimicking Paget’s Disease of the Breast
Asian Journal of Current Research in Clinical Cancer
Vol 5 Issue 1, 2025 | Ahmed Samaouel Chehad
Exploring the Radiosensitizing Effects of Tolmetin in Radiotherapy for Human Clonal Cancer Cells
Asian Journal of Current Research in Clinical Cancer
Vol 5 Issue 1, 2025 | Deep Kwatra

About GalaxyPub

Find out more

Our esteemed publisher is committed to advancing medical knowledge through rigorous research dissemination. We exclusively accept submissions related to the field of medicine.

Our journals provide a platform for clinicians, researchers, and scholars to share groundbreaking discoveries, clinical insights, and evidence-based practices. By maintaining this specialized focus, we ensure that their publications contribute significantly to the advancement of healthcare worldwide.