Written by Frans H Rutten
Published on Vol 2 , 2022
One of the most common chronic cardiovascular conditions that contributes to hospitalization, morbidity, and death among all heart patients is heart failure. The chance of developing heart failure is about 20% higher during one’s lifespan. Symptomatic forecasts typically lack specificity and are seldom able to distinguish heart failure from other illnesses. Due to its financial and medical strain on the healthcare system, this disease poses a dilemma. However, the treatment and presentation of a
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It has previously been shown that using dental implants for oral rehabilitation has generally produced favorable short- and long-term outcomes during the last few years. Implant success is hampered by the significant risk of postoperative infection caused by local environmental variables. For implant success, postoperative infection is necessary to be addressed as soon as feasible. We searched Medline, Pubmed, Embase, NCBI, and Cochrane databases to find information about the causes and mechanis
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Written by Ehdaa Ali Al-Abbad
Published on Vol 2 , 2022
Atypical pneumonia refers to a group of lower respiratory tract infections caused by specific respiratory pathogens that differ clinically and radiologically from typical bacterial community-acquired pneumonia (CAP). These infections involve both zoonotic and non-zoonotic transmission routes, with non-zoonotic cases being more common. A key distinguishing feature of atypical CAP is its frequent extrapulmonary involvement, which distinguishes it from the classic presentation of CAP. Therefore, re
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A root perforation is any situation, whether pathologic or the consequence of an accident, that causes a direct connection between the pulp and periodontal tissue due to iatrogenic dental caries or reabsorption. This study aimed to determine the clinical characteristics and efficacy of MTA, biodentine, and GIC in mending root perforations. Articles were selected from the previously published scientific articles, and inclusion and exclusion criteria were met to ensure that only articles with pert
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Written by Ravindra Ambardekar
Published on Vol 2 , 2022
Between 5% to 12% of people will get genitourinary stones throughout their lives. Men are more likely to develop calculus than women. Based on data from the Indian population, 12% of people have urinary calculi, and half of them lose their kidney’s ability to function. One prevalent ailment that urologists and surgeons see in emergencies is symptomatic urolithiasis. The most common location for ureteric calculus is the bottom third or distal ureter. This study compared the effectiveness of watch
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Written by Tetiana Martyshuk
Published on Vol 2 , 2022
This study aimed to investigate the hepatoprotective effects of potassium 2-((4-amino-5-(morpholinomethyl)-4H-1,2,4-triazole-3-yl)thio)acetate’s on tetracycline and viral hepatitis models in chickens. The intact Cobb 500 cross-broiler chickens were subjected to a biochemical analysis of their blood and liver serum. According to the specified specifications, each group of chickens was housed independently in a distinct cell in the same room with the same climatic characteristics. It was found tha
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Written by Muhammad Osama Yaseen
Published on Vol 2 , 2022
During severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the chance of suffering acute kidney injury (AKI) increases significantly. Therefore, the present study aimed to conduct a comprehensive pharmacotherapeutic evaluation of AKI in patients with coronavirus. From July to August 2021, a retrospective cohort study was conducted on coronavirus patients hospitalized at the Institute of Kidney Diseases, Hayatabad Medical Complex in Peshawar, Pakistan. Demographics, diagnosis,
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Bromide 1-( β -phenylethyl)-4-amino-1,2,4-triazolium (Hypertril) exhibits both beta-blocking and nitric oxide–mimetic activities and belongs to toxicity class IV. These pharmacological features make Hypertril a promising therapeutic agent for cardiovascular disorders. The present study aimed to evaluate the cardioprotective properties of Hypertril by assessing its impact on the morpho-functional characteristics of the myocardium in a rat model of chronic heart failure (CHF). Experimental CHF was
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Written by Maya van Dijk
Published on Vol 2 , 2022
This study aimed to create two tailored versions of the Communication Assessment Tool (CAT) suitable for community pharmacy settings and to conduct a preliminary evaluation on a selected sample. Two CAT versions were developed specifically for community pharmacists. Psychometric properties, including validity and reliability, were assessed. Construct validity of individual tool items was examined through confirmatory factor analysis, while reliability was measured using Cronbach’s alpha. Interna
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The pharmacopeial limit test for aluminum in citric acid intended for dialysate production commonly relies on solvent extraction with 8-hydroxyquinoline followed by fluorescence measurement. However, fluorescence intensity (F.I.) readings from citric acid extracts have frequently proven unreliable, often registering lower values than even the blank solution. This study aimed to investigate the impact of the citric acid matrix on the accuracy of the test. A comparison between standard aluminum so
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Written by Linnea Jansson
Published on Vol 2 , 2022
Following the introduction of Indonesia’s Universal Health Coverage (UHC) policy, the drug procurement mechanism shifted to an e-catalog system. However, the consequences of this transition for the country’s pharmaceutical industry remain uncertain and insufficiently examined. This study aims to evaluate how the UHC policy has influenced drug pricing practices within Indonesia’s pharmaceutical sector. Data were collected from three pharmaceutical companies that successfully won e-catalog tenders
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The primary obstacle to implementing pharmaceutical care was identified as limited access to patient medical records (90.6%). Most participants (93.0%) supported the development of a website offering pharmaceutical care services, and 45.1% indicated they would be willing to pay for such a service if available. Additionally, a large majority (89.8%) agreed that establishing a comprehensive patient data database could reduce medical errors. Evaluation of the four domains of pharmaceutical care—tec
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Written by Isabelle Moreau
Published on Vol 2 , 2022
Despite extensive research, the study of metabolic syndrome and its integration with other pathological conditions remains highly relevant. The complex interplay of various pathogenic mechanisms necessitates the development of new diagnostic and therapeutic tools. Drone brood homogenate, a compound with a multifaceted chemical composition, shows considerable promise for contemporary research. Its broad safety profile and applicability across different age groups further highlight its potential a
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Written by Noah Williams
Published on Vol 2 , 2022
Assessing service quality is crucial for determining how well healthcare services meet patient expectations. This review explores patient satisfaction with clinical pharmacy services and the factors shaping it. A comprehensive search of MEDLINE and EBSCO databases was conducted using the keywords “patient satisfaction,” “pharmacy service,” “hospital pharmacy service,” and “clinical pharmacy service.” Studies were included if they were original research, full-text, in English, and published betwe
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Written by Ella Martinez
Published on Vol 2 , 2022
In developing countries, healthcare expenditures have increased disproportionately compared to the financial resources provided by the government. Challenges related to inventory management and pharmaceutical market regulation have also been identified. To address these issues, we performed an ABC-VEN classification of the medicines stocked at Can Tho Dermatological Hospital (CTDH) between 2016 and 2020, aiming to provide evidence-based insights to help policymakers improve the efficiency of the
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Written by Ryota Nakamura
Published on Vol 2 , 2022
Two environmentally friendly, quick, and straightforward non-extractive spectrophotometric techniques have been developed for the quantitative estimation of valsartan in tablet formulations. The procedures rely on the formation of ion-pair complexes between valsartan and the acidic dyes bromophenol blue (BPB) and methyl red (MR). The drug interacts selectively with these dyes, generating colored complexes—yellow with BPB at pH 5.5, showing maximum absorbance at 424 nm, and red with MR at pH 4.3,
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Written by Marcus Johnson
Published on Vol 2 , 2022
Platinum-based complexes represent some of the most widely used anticancer agents. This study aims to collect, analyze, and comparatively evaluate clinical trials and therapeutic indications of currently approved platinum derivatives, including Cisplatin, Carboplatin, Oxaliplatin, Nedaplatin (Japan), Lobaplatin (China), Heptaplatin (North Korea), and Satraplatin. Another objective is to summarize the historical development of these drugs and to compare their pharmacokinetic properties, adverse e
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