Written by Gonçalo Januário
Published on Issue 1 Vol 2, 2022
Glioblastoma multiforme (GBM) is the most common form of primary malignant brain tumor in the central nervous system (CNS). While these tumors are commonly found in supratentorial areas, they rarely occur in infratentorial regions, accounting for approximately 0-3.4% of all primary GBMs. The occurrence of GBMs in adults is relatively rare, with even fewer cases reported in the elderly population. Typically, these tumors present as rapidly expanding lesions in the posterior fossa, often leading t
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Written by Ayse Nur Akatli
Published on Issue 1 Vol 2, 2022
This study focused on investigating the roles of p16INK4a, p14ARF, and p53 proteins in the development of squamous cell carcinoma of the lip. A total of 46 tissue samples were analyzed, which included 19 cases of squamous cell carcinoma of the lip, 14 cases of actinic cheilitis, and 13 samples of normal lip mucosa. The study also evaluated protein expression in the epithelial tissue surrounding the tumors. Notably, p16INK4a levels were significantly higher in actinic cheilitis compared to normal
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Written by Abubakr Mohammed Ali Nasr
Published on Issue 1 Vol 2, 2022
Choriocarcinoma is a highly aggressive neoplasm of trophoblastic origin, which can be classified as either gestational or non-gestational. The majority of cases are gestational, arising from either normal or abnormal pregnancies. This review examines the prevalence and risk factors of choriocarcinoma by analyzing the available literature. The research team conducted a comprehensive search of databases such as ScienceDirect, PubMed, EBSCO, Web of Science, Cochrane Library, and Scopus. They screen
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Written by Lauro FigueroaValverde
Published on Issue 1 Vol 2, 2022
While various drugs are available for the treatment of cancer, many of them are associated with side effects such as high blood pressure, liver damage, and erectile dysfunction. In the search for safer treatment options, some dibenzo derivatives have shown potential against cancer. However, conflicting reports indicate that certain dibenzo compounds might worsen the disease. This inconsistency could be due to structural differences among the dibenzo derivatives. To clarify this, the present stud
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Written by Mahmoud Mohamed Ahmed
Published on Issue 1 Vol 2, 2022
Numerous studies, including our previous research, have investigated the effects of different plasma sources and their respective doses on both healthy and cancerous cells. These studies aimed to interpret the potential mechanisms behind cancer treatment involving plasma and its interactions with cells. Plasma has been shown to play an important role in the outcomes of cancer cell treatment through several investigations, including genetic, biochemical, and immunological analysis. This body of w
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