Written by Dani Stanbouly
Published on Vol 2 Issue 1, 2022
Untreated craniosynostosis can lead to a variety of problems, including cognitive and psychological problems, as well as craniofacial deformities. However, its association with epileptic seizures is still unclear. This review aimed to assess the occurrence of epilepsy among people with craniosynostosis. Several databases, including the Cochrane Library, Science Direct, Web of Science, EBSCO, and PubMed, were searched for relevant studies. Rayyan QCRI was used to screen the titles and abstracts o
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Written by Miere Groza Florina
Published on Vol 2 Issue 1, 2022
Recent research increasingly highlights the connection between diet, the gut microbiome, and overall human health. It has been established that the gut microbiome functions as an independent “organ” and its metabolic activity influences the overall metabolism of the body. This paper emphasizes the key roles of the gut microbiome, its composition, and its importance in maintaining the body’s health, as well as the changes that occur under pathological conditions. Our study includes recent in vivo
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Written by Asma Ayed Alanazi
Published on Vol 2 Issue 1, 2022
Klinefelter syndrome is the most common sex chromosome anomaly, occurring in approximately 1 in 660 males, yet fewer than 30% of individuals are diagnosed. This low diagnosis rate is due to the wide variability in the phenotypic presentation of the condition. The failure to detect Klinefelter syndrome early can lead to significant health complications, including primary hypogonadism, infertility, and an elevated risk of various cancers and other systemic diseases. This study aimed to review the
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Written by Marc Evans
Published on Vol 2 Issue 1, 2022
Chronic kidney disease (CKD) encompasses a variety of kidney function and structural abnormalities, posing a significant global health challenge. Early detection and management are critical, with guidelines from 2002 outlining CKD classification based on severity, which is determined by factors such as glomerular filtration rate (GFR), clinical diagnosis, and albuminuria. Routine laboratory tests play a key role in detecting CKD at early stages. Effective treatments are available to slow disease
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Written by Ahmed O. Babalghith
Published on Vol 2 Issue 1, 2022
Cardiac remodeling involves alterations in gene expression, molecular, cellular, and interstitial changes that ultimately affect heart function. Coenzyme Q10 (CoQ10) plays a critical role in the mitochondrial electron transport chain, which is essential for ATP production. This study aimed to evaluate the effect of CoQ10 on myocardial infarction (MI) in male rats induced by isoproterenol (ISO). The rats were divided into four groups: control, CoQ10-treated, ISO-treated, and CoQ10+ISO-treated. Va
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Written by Lucas Martin
Published on Vol 2 Issue 1, 2022
Rates of Erectile Dysfunction (ED) continue to rise each year. Synthetic pharmacological agents used for ED frequently produce unwanted reactions, and their therapeutic performance is limited. Within Indonesia, several native plants have traditionally been used to manage ED symptoms. This review seeks to compile updated scientific data on Indonesian medicinal plants with potential efficacy against ED and to clarify their molecular actions using a systematic review and a Pharmacological Network f
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Written by Alessandro Marino
Published on Vol 2 Issue 1, 2022
Enterococcus faecalis plays a major role in root canal infections. This investigation sought to compare the ability of two intracanal pastes—one containing calcium hydroxide with saline and the other containing calcium hydroxide with propolis—to eradicate E. faecalis from contaminated canals. Twenty extracted first premolars with single roots and single canals were randomly divided into two groups of 10 teeth. Each canal was inoculated with a prepared bacterial suspension grown aerobically at 37
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Written by Rajiv Sharma
Published on Vol 2 Issue 1, 2022
Complementary and alternative medicine (CAM) has emerged as people seek additional ways to alleviate pain and manage illnesses. Its usage is increasing among populations worldwide, including in both developed and developing countries, and notably among surgical patients. Understanding the perceived adverse effects, safety perceptions, and factors influencing CAM use is essential to inform advocacy for proper regulation. A cross-sectional study was conducted among surgical outpatients at a tertia
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Written by Miguel Alvarez
Published on Vol 2 Issue 1, 2022
Because complementary, alternative, and integrative medicine (CAIM) is frequently used alongside standard perioperative treatments and may offer certain benefits, it is important to understand how CAIM is perceived within surgical contexts. A survey was distributed to authors who had published in surgical journals. A total of 40,074 researchers and clinicians were invited. The questionnaire collected demographic information and explored perspectives on CAIM. There were 599 completed surveys, and
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Written by John Peterson
Published on Vol 2 Issue 1, 2022
Clostridioides difficile infection poses major clinical and operational challenges. Hospitals have both quality and economic motivations to manage CDI effectively. Universal admission screening is rarely recommended, and prior modeling efforts often relied on limited samples, overly complex feature sets, or black-box techniques. Our goal was to create models using patient information to estimate the likelihood of a positive test with strong discrimination, clear interpretability, and a practical
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Written by Jean Martin
Published on Vol 2 Issue 1, 2022
Perioperative pharmacy services are designed to enhance medication safety and patient-oriented care during surgical procedures. This study set out to review drug use and identify potential drug–drug interactions (pDDIs) within a general surgery department. A prospective, descriptive study was performed in a general surgery service of a Turkish hospital. Individuals admitted for any surgical intervention and hospitalized for at least 24 hours were included. Information regarding chronic medicatio
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Written by Hiroshi Tanaka
Published on Vol 2 Issue 1, 2022
Paramedics encounter numerous occupational hazards, including ergonomic, physical, psychological, and biochemical risks. This work examines the types of discomfort paramedics experience during in-ambulance procedures, highlighting their adverse influence on musculoskeletal loading and providing a basis for ergonomic and organizational improvements. Non-invasive MyoMotion and EMG assessments were used to evaluate musculoskeletal strain during common medical interventions performed both at rest an
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Written by Ahmed Hassan
Published on Vol 2 Issue 1, 2022
Coridius chinensis, a traditional medicinal insect in China, consists of the dried whole insect from the Pentatomidae family (Coridius chinensis Dallas). Recent pharmacological research has isolated and characterized over 100 bioactive small molecules from this species. Experimental studies have revealed multiple pharmacological effects, including pain relief, antioxidant activity, anticancer potential, anticoagulation, and antibacterial properties. Traditionally, it has been used in Chinese med
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Written by Chen Yu
Published on Vol 2 Issue 1, 2022
This study emphasizes the importance of medicinal plants as a key component of global biodiversity conservation and human health. It specifically stresses the necessity for precise identification of medicinal plant species to ensure their sustainable protection and proper application. Traditional classification techniques face difficulties due to the intricate nature of plant characteristics and the scarcity of annotated datasets. To overcome these limitations, this work introduces a deep learni
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