Written by Dani Stanbouly
Published on Issue 1 Vol 2, 2022
Untreated craniosynostosis can lead to a variety of problems, including cognitive and psychological problems, as well as craniofacial deformities. However, its association with epileptic seizures is still unclear. This review aimed to assess the occurrence of epilepsy among people with craniosynostosis. Several databases, including the Cochrane Library, Science Direct, Web of Science, EBSCO, and PubMed, were searched for relevant studies. Rayyan QCRI was used to screen the titles and abstracts o
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Written by Miere Groza Florina
Published on Issue 1 Vol 2, 2022
Recent research increasingly highlights the connection between diet, the gut microbiome, and overall human health. It has been established that the gut microbiome functions as an independent “organ” and its metabolic activity influences the overall metabolism of the body. This paper emphasizes the key roles of the gut microbiome, its composition, and its importance in maintaining the body’s health, as well as the changes that occur under pathological conditions. Our study includes recent in vivo
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Written by Asma Ayed Alanazi
Published on Issue 1 Vol 2, 2022
Klinefelter syndrome is the most common sex chromosome anomaly, occurring in approximately 1 in 660 males, yet fewer than 30% of individuals are diagnosed. This low diagnosis rate is due to the wide variability in the phenotypic presentation of the condition. The failure to detect Klinefelter syndrome early can lead to significant health complications, including primary hypogonadism, infertility, and an elevated risk of various cancers and other systemic diseases. This study aimed to review the
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Written by Marc Evans
Published on Issue 1 Vol 2, 2022
Chronic kidney disease (CKD) encompasses a variety of kidney function and structural abnormalities, posing a significant global health challenge. Early detection and management are critical, with guidelines from 2002 outlining CKD classification based on severity, which is determined by factors such as glomerular filtration rate (GFR), clinical diagnosis, and albuminuria. Routine laboratory tests play a key role in detecting CKD at early stages. Effective treatments are available to slow disease
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Written by Ahmed O. Babalghith
Published on Issue 1 Vol 2, 2022
Cardiac remodeling involves alterations in gene expression, molecular, cellular, and interstitial changes that ultimately affect heart function. Coenzyme Q10 (CoQ10) plays a critical role in the mitochondrial electron transport chain, which is essential for ATP production. This study aimed to evaluate the effect of CoQ10 on myocardial infarction (MI) in male rats induced by isoproterenol (ISO). The rats were divided into four groups: control, CoQ10-treated, ISO-treated, and CoQ10+ISO-treated. Va
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