Written by Ankita Wal
Published on Vol 3 Issue 1, 2023
Irritable bowel syndrome (IBS) is a widespread digestive condition characterized by visceral hypersensitivity and changes in bowel habits. It is primarily influenced by factors such as smoking, stress, changes in the gut microbiota, and genetic variations. Since no specific cure currently exists for IBS, it is crucial to evaluate the benefits and limitations of current animal models of IBS, to utilize them effectively, and to develop improved models for drug research and development. This paper
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Written by Luminita Fritea
Published on Vol 3 Issue 1, 2023
COVID-19 often triggers a strong inflammatory response, which leads to significant changes in immune system cell counts. In this study, we analyzed the following blood biomarkers from COVID-19 patients: white blood cells (WBC), monocytes, neutrophils, lymphocytes, eosinophils, C-reactive protein (CRP), basophils, and blood sugar levels (glycemia). We examined various comparisons, correlations, and ratios among these markers to better understand the relationship between pre-existing health condit
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Written by Laysen Ramilevna Salikhova
Published on Vol 3 Issue 1, 2023
Approximately 11% of newborns experience hypoxia, which is a primary factor contributing to premature births, neonatal and fetal mortality, and various health complications. Fetal oxygen exchange occurs through the placenta, facilitated by erythrocytes. Consequently, fetal respiration is affected by the efficiency of erythrocyte passage through small capillaries. The elasticity, surface area, and permeability of the erythrocyte membrane directly affect the effectiveness of intrauterine respirati
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Written by Ankita Wal
Published on Vol 3 Issue 1, 2023
Myasthenia gravis is an autoimmune disorder caused by antibodies that attack the neuromuscular junction. These antibodies target and damage postsynaptic components by binding to the postsynaptic muscle end-plate, leading to disrupted signal transmission and resulting in muscle weakness and fatigue. Advances in understanding the immunological mechanisms behind myasthenia gravis have led to the development of targeted immunotherapies. This review examines the subgroups of myasthenia gravis, therap
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Written by Felicia Manole
Published on Vol 3 Issue 1, 2023
Allergic rhinitis, a common upper respiratory condition, imposes significant healthcare costs worldwide each year due to its widespread occurrence. This condition has become a major global health concern. In recent years, there has been increasing interest in the study of allergic rhinitis, particularly about its rising prevalence and its association with other conditions such as asthma. This review focuses on single nucleotide polymorphisms (SNPs) associated with allergic rhinitis. It examines
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Written by Carlos Pinto
Published on Vol 3 Issue 1, 2023
In China, clinicians often use Chinese patent medicines (CPMs) as supportive therapy for diabetic retinopathy (DR). This study employed a network meta-analysis (NMA) to evaluate the comparative efficacy and safety of three CPMs combined with calcium dobesilate (CD) and to identify the most effective adjunctive treatment for DR.A Bayesian NMA framework was applied to examine both therapeutic outcomes and safety profiles of different CPM regimens in DR. The review protocol was registered in PROSPE
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Written by Amir Khalil
Published on Vol 3 Issue 1, 2023
Lavandula stoechas L. (Ustukhuddūs) has long been employed in traditional medicine for managing neurological conditions such as dementia, yet conventional oral and topical formulations often fail to achieve optimal therapeutic effects. To overcome these limitations, this study developed matrix-type transdermal patches incorporating Ustukhuddūs hydro-alcoholic extract (UHAE) and essential oil (UEO) using a combination of hydrophilic hydroxyl propyl methyl cellulose (HPMC) and hydrophobic ethyl ce
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Written by Anders Johansson
Published on Vol 3 Issue 1, 2023
In traditional Chinese medicine (TCM) syndrome diagnosis research, the Delphi technique is often used to build expert consensus when evidence is limited and opinions differ. Despite its frequent use, there has been no systematic evaluation of how this method is conducted or reported in this context. This study investigates the consistency of Delphi method application and evaluates the quality of reporting in TCM research. A cross-sectional analysis was performed to identify studies utilizing the
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Written by Bekele Tadesse
Published on Vol 3 Issue 1, 2023
Controlled hypotension is frequently employed during Functional Endoscopic Sinus Surgery (FESS) to improve surgical field visibility. Intranasal (IN) administration of dexmedetomidine provides a noninvasive alternative with lower peak plasma concentrations and milder pharmacodynamic effects, including reduced hypotension, bradycardia, and sedation, compared to intravenous (IV) delivery. This study compared IN and IV dexmedetomidine in the context of hypotensive anesthesia for FESS.In a randomize
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Written by Narin Chaisakul
Published on Vol 3 Issue 1, 2023
To improve operational efficiency within the healthcare sector, this study explores the development of a medical information diagnostic platform leveraging swarm intelligence and evolutionary algorithms. The paper first reviews the current state of medical diagnostic platforms that integrate Chat Generative Pre-trained Transformer (ChatGPT) models with Internet of Things (IoT) technology. It then provides a detailed analysis of the strengths and limitations of employing swarm and evolutionary al
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Written by Juan Pérez
Published on Vol 3 Issue 1, 2023
Traditional herbal remedies and nutritional supplements are widely used to manage various health conditions, but many lack proper standardization and scientific validation for safety and effectiveness. In this research, multiple forms of traditional herbal medicines prescribed for specific diseases were collected from practitioners in various districts of Khyber Pakhtunkhwa, Pakistan. The samples were analyzed using atomic absorption spectroscopy to determine concentrations of heavy metals, trac
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Written by Daniel Svensson
Published on Vol 3 Issue 1, 2023
Bullying and peer victimization among students in medical and health sciences pose a serious public health concern, given their long-term psychological consequences and increased susceptibility to mental health disorders throughout life. This study employed a descriptive cross-sectional design to assess the prevalence of bullying and its association with self-esteem, anxiety, and depression among university students in Ras Al Khaimah, United Arab Emirates. A total of 369 participants from MBBS,
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Written by Paulo Mendes
Published on Vol 3 Issue 1, 2023
Job satisfaction is a key driver of employee productivity, yet when job demands exceed individual capabilities, stress can occur. Identifying the factors that cause dissatisfaction is essential to minimize work-related stress, which negatively affects healthcare service quality. Research exploring stress and job satisfaction among medical laboratory professionals (MLPs) remains limited. This study aimed to examine the relationship between job stress and satisfaction among MLPs in Omani hospitals
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Written by Mohammed Rahman
Published on Vol 3 Issue 1, 2023
Extensive research has explored how Chinese herbal formulations may slow the advancement of chronic kidney disease (CKD) by modulating colonic microflora and microbiota-derived metabolites. Despite this, it remains unclear whether FuZhengHuaYuJiangZhuTongLuo (FZHY) exerts regulatory effects on CKD that parallel those reported for AST-120.To address this question, we systematically compared the influence of FZHY and AST-120 on gut microbiota composition and plasma metabolomic profiles in a chroni
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