Written by Sun Ming
Published on Vol 5 Issue 2, 2025
Diabetes mellitus often leads to long-term complications that significantly affect patient health and survival. Among these complications, diabetic peripheral neuropathy (DPN) is the most common and can result in serious consequences if left undetected. Early identification through reliable screening methods is essential, and the Michigan Neuropathy Screening Instrument (MNSI) serves as a practical tool for this purpose in clinical practice. However, information regarding the occurrence and cont
Written by Tesay Gebru
Published on Vol 5 Issue 2, 2025
The study investigated how utilizing a 3D virtual application relates to academic performance in Peruvian medical students, while also exploring additional factors that could impact their academic outcomes.” We carried out a cross-sectional analytical study involving students enrolled in the Musculoskeletal System course in the first semester of 2019. Participants provided information through a structured data form and completed the adapted Self-Directed Learning Readiness Scale (SDLRS) by Fishe
Written by José Manuel Cruz
Published on Vol 5 Issue 2, 2025
During the COVID-19 pandemic, medical schools in low- and middle-income countries (LMICs) have faced numerous challenges in adopting online learning management systems (LMS). To address this, our medical school designed and implemented a tailored LMS for its students. This study aims to evaluate how medical students accept and benefit from the LMS, as well as to explore the factors that influence their engagement with online learning. This study employed a mixed-methods design, combining an onli
Written by Irakli Beridze
Published on Vol 5 Issue 2, 2025
Conducting research in emergency settings is crucial for advancing knowledge and improving the management of acutely ill patients. Nonetheless, the urgent and complex nature of these situations presents significant ethical challenges for researchers who handle emergent cases. This study sought to explore the attitudes of healthcare providers (HCPs) in Jordan regarding exceptions from informed consent (EFIC) and their willingness to enroll patients in emergency research. A quantitative study was
Written by Josef Mwinyi
Published on Vol 5 Issue 2, 2025
This study aimed to evaluate the cleaning practices of non-critical medical equipment (NCME) among nurses working at Debre Tabor Comprehensive Specialized Hospital (DTCSH) in north-central Ethiopia during the COVID-19 pandemic. A facility-based cross-sectional study was carried out at Debre Tabor Comprehensive Specialized Hospital (DTCSH), Ethiopia, from July 5 to August 5, 2020. The study was conducted in inpatient and outpatient units of the hospital. The study involved observations of 76 rand
Written by Abdoulaye Traoré
Published on Vol 5 Issue 2, 2025
The socio-economic consequences of unexpected health problems among mine workers are substantial. In Ghana’s artisanal mining sector, miners typically bear the full responsibility for their own health care, making it crucial to understand the factors that shape their self-care practices. This study employed a cross-sectional survey of 500 artisanal gold miners and used a nested binary logistic regression model to examine how working conditions influence miners’ decisions to voluntarily undertake
Written by Sibusiso Khumalo
Published on Vol 5 Issue 2, 2025
Diabetes mellitus has emerged as the fastest-growing global health crisis of the 21st century, with the Middle East and North Africa region exhibiting the highest prevalence worldwide. As future healthcare professionals, medical students play a crucial role in addressing this challenge, making it essential to assess, update, and strengthen their knowledge of the disease. During the Syrian conflict, a cross-sectional survey was conducted at the Syrian Private University (SPU) in Damascus in Novem
Written by Nimal Perera
Published on Vol 5 Issue 2, 2025
hutan does not have its own medical school, and therefore Bhutanese medical students pursue their training in Sri Lanka, Bangladesh, and India. When medical institutions in these countries closed during the initial COVID-19 outbreak in March–April 2020, the students were brought back to Bhutan. After repatriation, they were placed in government-managed quarantine facilities for 21 days. This study examined their COVID-19–related knowledge acquired through self-learning, as well as their attitude
Written by Ahmed Abdalla
Published on Vol 5 Issue 2, 2025
The COVID-19 pandemic has led to substantial modifications in the undergraduate medical curriculum, with numerous in-person clinical sessions being replaced by online teaching methods. This study seeks to examine the relationship between medical students’ stress levels during the pandemic and their performance in the final examinations. This cross-sectional study utilized a questionnaire-based approach to assess students’ stress levels, measured using the COVID-19 Student Stress Questionnaire (C
Written by Victor Nascimento
Published on Vol 5 Issue 2, 2025
The novel coronavirus primarily spreads through airborne droplets and contaminated surfaces. To limit transmission, the widespread use of face masks and gloves has become a daily practice, resulting in a significant rise in environmental waste. Improper disposal of these items in public spaces may further facilitate virus transmission. Despite this growing concern, studies exploring public perceptions of managing pandemic-related masks and gloves remain scarce. This study investigates public awa
Written by Abdulaziz Al-Harbi
Published on Vol 5 Issue 2, 2025
Postgraduate medical trainees are exposed to intense stressors that frequently undermine their overall happiness and life satisfaction. While prior research has established that strong social networks can bolster psychological well-being, exactly how and under what conditions this occurs in medical postgraduates has remained largely unknown. This research investigated the pathways linking perceived social support to subjective well-being in this specific group, with a particular focus on two key
Written by Hamidou Diallo
Published on Vol 5 Issue 2, 2025
Technology provides new opportunities for learning, including the use of recorded lectures (RLs). This study aimed to assess how effective online RLs are for learning within clinical courses at a School of Medicine. The research was conducted in four phases: (i) a pre–post uncontrolled study to measure knowledge acquisition from RLs, (ii) a non-randomised crossover study comparing learning when RLs were viewed before or after a face-to-face lecture (FL), (iii) focus groups to explore students’ p
Written by João Silva
Published on Vol 5 Issue 2, 2025
Small extracellular vesicles originating from human mesenchymal stem cells (MSC-sEVs) exhibit notable immunomodulatory and tissue-regenerative properties. Nonetheless, the absence of well-defined specific markers for these vesicles remains a critical barrier to their effective clinical deployment. In the present work, proteomic profiles of MSC-sEVs generated from three different cellular origins were examined in parallel. Candidate surface antigens commonly expressed by MSCs were identified base
Written by Emma Wilson
Published on Vol 5 Issue 2, 2025
Acute myeloid leukemia (AML) is an aggressive hematological cancer and ranks among the most frequent leukemias observed in adults. Although new targeted treatments have recently been developed and approved, the emergence of drug resistance continues to present a serious therapeutic barrier. This investigation utilized an unbiased CRISPR-Cas9 gene knockout screen in AML cell lines to discover unrecognized factors contributing to resistance against the approved FLT3 inhibitor gilteritinib. The scr
Written by Mark Anderson
Published on Vol 5 Issue 2, 2025
Clear cell renal cell carcinoma (ccRCC) represents the predominant histological variant of renal cell carcinoma (RCC) and necessitates precise pathological grading to inform accurate prognostic assessment. Nevertheless, conventional grading techniques depend primarily on the subjective evaluations of pathologists, which frequently result in considerable inconsistency. Although generative artificial intelligence (GenAI) has exhibited encouraging capabilities in medical imaging, its integration in
Written by Sara Al-Fahd
Published on Vol 5 Issue 2, 2025
Heart failure with preserved ejection fraction (HFpEF) comprises over half of heart failure presentations, although the availability of proven treatments is restricted owing to the condition’s considerable clinical variability. The current investigation sought to uncover discrete HFpEF subtypes by applying a machine learning algorithm and to assess how treatment outcomes vary among these phenogroups. Data from 2147 patients admitted with heart failure and left ventricular ejection fraction (LVEF
Written by Youssef Hariri
Published on Vol 5 Issue 2, 2025
Brain-computer interfaces (BCIs) utilizing motor imagery (MI) have emerged as a promising rehabilitation strategy for individuals recovering from stroke. Classification techniques founded on Riemannian geometry are commonly adopted in MI-BCI systems because of their exceptional robustness and capacity for generalization. Nonetheless, existing algorithms exhibit limitations in clustering performance, primarily due to clustering criteria that are inadequately adapted to the specific characteristic
Written by David Osei
Published on Vol 5 Issue 2, 2025
Three-dimensional (3D) bioprinting constitutes a groundbreaking approach for constructing biomimetic tissue structures, holding substantial promise for tissue engineering and regenerative medicine. A key obstacle, however, lies in creating environmentally sustainable bio-inks that deliver strong printability, robust mechanical performance, and long-term stability in physiological environments, all while avoiding expensive and laborious chemical alterations. This research introduces a practical a
Written by Kristian Eriksen
Published on Vol 5 Issue 2, 2025
Strategies to avert type 1 diabetes (T1D), a condition driven by autoimmune processes and necessitating continuous lifelong therapy, are still constrained. This investigation aimed to uncover new candidate therapeutic targets for T1D by employing Mendelian randomization together with colocalization analyses that relied on genetic instruments originating from immune cells. We identified cis-acting genetic variants across 14 transcriptomic datasets to instrument the expression of 8998 genes profil
Written by Mikko Lahtinen
Published on Vol 5 Issue 2, 2025
Cancer stem cells possess highly adaptable metabolic characteristics. Nonetheless, the precise mechanisms linking specific metabolic routes to the sustained stemness of gastric cancer cells are not well characterized. The present work identifies the critical contribution of serine hydroxymethyltransferase-2 (SHMT2) and serine to the functional interaction between one-carbon metabolism and lipid metabolism that supports stemness maintenance in gastric cancer. In clinical specimens, SHMT2 was stro
Written by Omar Zayed
Published on Vol 5 Issue 2, 2025
Radiotherapy-induced skin defect (RISD) represents a major adverse effect of radiation treatment, marked by prolonged oxidative stress and repeated overproduction of reactive oxygen species (ROS) that obstruct physiological tissue regeneration. The absence of a reliable standardized animal model, however, continues to impede advancement in this field. To address this issue, we propose an innovative strategy for remodeling the RISD microenvironment through a sequential process involving initial R
Written by Wei Zhang
Published on Vol 5 Issue 2, 2025
Osteosarcoma (OS) represents the predominant primary malignant bone tumor among children and young adults and continues to present major therapeutic obstacles. This investigation explored the involvement of exosomes, which serve as critical mediators of cell-to-cell signaling, in driving OS advancement and pinpointed promising therapeutic candidates. Experiments performed in both in vitro cellular systems and in vivo animal models revealed that exosomes secreted by OS cells substantially acceler
Established in 2019, Galaxy Publication stands as a global academic publishing house focused on advancing scholarly work across medicine, nursing, and health sciences. Through its network of peer-reviewed journals, the organization brings together original research and academic contributions from scholars around the world, creating a shared space for knowledge exchange and intellectual collaboration.
