Volume 4, Issue 2 (2024)

This systematic review aimed to evaluate the effectiveness of allogenic bone block grafts in the reconstruction of the maxillary alveolar ridge.A comprehensive search of PubMed, Cochrane Library, and Google Scholar was performed, complemented by manual searches. Studies included were randomized controlled trials (RCTs) and prospective clinical trials (non-RCTs) published up to December 2022, reporting outcomes of allogenic bone blocks used for maxillary alveolar ridge augmentation. The primary o

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This study aimed to assess the bone healing capacity of 1-, 2-, and 3-wall defects after alveolar ridge preservation (ARP) and to determine the effectiveness of ARP in managing compromised extraction sites. Eight beagle dogs were used, with three defect types (1-, 2-, and 3-wall) randomly assigned to the maxillary second, third, and fourth premolars. Each defect was created at either the mesial or distal root of a hemi-sectioned tooth, with the opposing root retained to allow histomorphometric c

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The injection moulding technique (IMT) offers a conservative, minimally invasive approach for dental restorations, enabling precise application of thin, flowable composite into a transparent silicone mould. Its fluid consistency allows complete adaptation to the mould and natural tooth surfaces, often avoiding the need for any tooth preparation and preserving tooth integrity. Using an etch-and-rinse protocol, IMT is highly reproducible and particularly advantageous following orthodontic treatmen

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Periodontitis is a chronic inflammatory disease driven by complex interplays between a dysbiotic oral microbiome and a dysregulated host inflammatory response that results in the destruction of the tooth-supporting apparatus. Among the inflammatory cells involved in the pathogenesis of periodontitis, macrophages are recruited early on to sites of periodontal infection. These cells can polarize in different phenotypes that mediate the initiation and resolution of inflammatory responses, as well a

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The Korea Oral Biobank Network (KOBN) was established in 2021 as a branch of the Korea Biobank Network under the Korea Centers for Disease Control and Prevention to provide infrastructure for the collection, management, storage, and utilization of human bioresources from the oral cavity and associated clinical data for basic research and clinical studies. To address the need for the unification of the biobanking process, the KOBN organized the concept review for all the processes. The KOBN estab

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The objective of this retrospective clinical study was to provide evidence supporting the adjunctive local application of doxycycline solution or minocycline ointment, in conjunction with drainage, for the treatment of acute periodontal abscesses. The study included 63 patients who had received treatment for acute periodontal abscesses through drainage supplemented with 1 of 3 types of adjunctive medications during their initial visit (visit 1; baseline): 1) saline irrigation (the control group)

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Our pilot study showed that a 3-dimensional dual drug delivery scaffold (DDDS) loaded with Chinese herbs significantly increased the regenerated bone volume fraction. This study aimed to confirm the synergistic anti-inflammatory and osteogenic preclinical effects of this system. The targets and pathways of parthenolide and naringin were predicted. Three cell models were used to assess the anti-inflammatory effects of parthenolide and the osteogenic effects of naringin. First, the distance betwee

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Oral malodor is a major periodontal complaint, but the best method for assessing the halitosis grade is still undefined. The primary objective of the study was to detect the halitosis grade in the exhaled breath using the three distinct techniques and to compare the readings with different clinical indices to find out the best method of halitosis grading. A total of 90 patients with chronic periodontitis having oral malodor were included in the study. The subjective assessment of the exhaled bre

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A combination of activin and bone morphogenetic protein-2 (BMP-2), termed AB204, has been shown to improve osteogenic potential with fewer side effects than BMP-2 alone. This study was performed to evaluate the effect of AB204 on periodontal tissue regeneration in a dog buccal dehiscence model. Buccal dehiscence defects were created on the maxillary premolars (P1, P2, and P3) of 6 mongrel dogs. After 5 weeks, the dogs were randomly assigned to 1 of 3 groups: the control, collagen matrix (CM), an

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Hormonal fluctuations, primarily in progesterone and estrogen during the menstrual cycle, may influence periodontal tissues, with inflammatory cytokines playing a crucial role. Therefore, our primary objective was to assess clinical periodontal parameters and measure levels of interleukin (IL)-1β, IL-6, and tumor necrosis factor (TNF)-α in gingival crevicular fluid (GCF) throughout the menstrual cycle. This longitudinal prospective study was conducted from February to April 2022 and included 50

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Mucogingival defects (MGDs), such as dental root recessions, decreased vestibular depth, and absence of keratinized tissues, are commonly seen in dental clinics. MGDs may result in functional, aesthetic, and hygienic concerns. In these situations, autogenous soft tissue grafts are considered the gold-standard treatment. This study compares the healing process of free gingival grafts (FGGs) to bacterial cellulose matrix (BCM) and human acellular dermal matrix (ADM) seeded with fibroblasts from cu

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