Several regulatory bodies throughout the world have produced and approved several COVID-19 vaccines for use in emergencies. In addition to providing a centralised database of suspected adverse reactions and safety profiles for these vaccinations, the aim is to compare the safety and side effects of approved COVID-19 vaccines in Saudi Arabia. As part of this cross-sectional study, an online questionnaire was used to survey 633 vaccinated Saudi Arabian citizens. Their ages ranged from 15 to 85 years. According to the study, 33% of individuals had COVID-19 before immunisation, and 55% of participants had the virus. 10% of the study participants had two or more associated comorbidities, most commonly diabetes mellitus, respiratory issues, and hypertension. Fatigue, headaches, fever, myalgia, arthralgia, and injection site discomfort, tenderness, and swelling are the most common adverse effects of these vaccines, especially following the initial dosage. Systemic adverse effects were frequently observed in young female participants aged 15 to 30 years. According to age, gender, comorbidities, and vaccine type, this study makes assumptions about a database regarding the likelihood of experiencing COVID-19 vaccine side effects. Further research is needed to better understand the relationship between risk factors and developing negative outcomes.
