There is no written advice tool for the use of subcutaneous anticoagulants in patients with COVID-19, so this study aimed to develop and validate one. A prospective cohort study was conducted with patients and expert panels, and hospital chemists used the content validity index (I-CVI), scale-level-CVI (S-CVI), and universal acceptance (UA) to validate the tool. The item acceptance index (IAI) and universal acceptance (UA) were used to assess the patients’ face validity. The mean age of hospital chemists (n = 26) was 35.82.9 years, and the majority were Chinese (n = 20, 76.9%) and female (n = 18, 69.2%). Hospital chemists evaluated every item pertinently (n = 18, 100%), with I-CVIs ranging from 0.96 to 1.00. I-CVI average, or the average proportion of items (sum of I-CVI/number of items: 17.88/18) was 0.99. High content validity was demonstrated with the reported S-CVI/UA (sum of UA/no. of items: 15/18) being 0.83 and S-CVI/Average (sum of I-CVI/no. of items: 17.88/18) being 0.99. The mean age of the 28 patients who participated in the face validation of the construct was 38.0±9.8 years, with the majority being female (n = 19, 67.9%), Malay (n = 46.4%), and tertiary educated (n = 20, 71.4%). All items were marked as relevant (n = 18, 100%), with the IAI ranging from 0.93 to 1.00, indicating that patients accepted each construct item; the average proportion of items was reported as 0.99 (sum of IAI/no. of items: 17.82/18), indicating excellent acceptance and content comprehension among patients. The counselling tool that was developed is suitable for anticoagulant education among COVID-19 patients.
