Magnolia officinalis, a tree known for its bark, leaves, and flowers, contains phytochemicals that have garnered significant attention in recent research. Modern medicine increasingly incorporates plant extracts, rich in various classes of phytochemicals, either as replacements for traditional treatments or as complementary additions to enhance efficacy and minimize side effects. This study focuses on the extraction of oil from the leaves of M. officinalis, which was analyzed using GC-MS, revealing a predominance of monoterpenes (notably linalool and its derivatives) and sesquiterpenes (such as caryophyllene). These compounds are investigated for their potential therapeutic effects across a range of conditions, with a particular emphasis on their mechanisms of action. In addition to chemical analysis, the leaves were examined macroscopically and microscopically. The antimicrobial properties of the extracted oil were tested against both gram-positive and gram-negative bacteria. To address the challenges of oil degradation over time and its limited bioavailability when taken orally, the oil was encapsulated using the coacervation method, a quick and cost-effective technique. The encapsulation protects the oil’s properties and improves its bioavailability. Future research will focus on evaluating the bioavailability of the encapsulated oil through oral administration and monitoring its stability during storage.
