Written by Carina Bona
Published on Issue 2 Vol 4, 2024
This study provides a 2024 update on survival outcomes and the frequency of hematologic complications, specifically lymphocytopenia, neutropenia, and thrombocytopenia, in patients treated with axicabtagene ciloleucel (axi-cel) and tisagenlecleucel (tisa-cel) CAR-T cell therapies. The study examined 56 patients diagnosed with diffuse large B-cell lymphoma who underwent CAR-T cell therapy from 2019 to March 2024. Among them, 34 patients received axi-cel (group A), and 22 patients were treated with
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Written by Tahir Mehmood Khan
Published on Issue 2 Vol 4, 2024
The purpose of this research is to analyze the epidemiological trends of female-specific cancers in Malaysia. The review included studies from various sources, including the Asian Pacific Journal for Cancer Prevention, as well as databases like PubMed, Medline, Wiley Online Library, and ProQuest Central. The selected studies were published in various languages and covered all types of trials on patients of any age, between 1980 and 2016. The findings highlighted that Chinese women had the highes
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Written by Liping Xie
Published on Issue 2 Vol 4, 2024
This study investigated the biological effects of coriander root extract on gastric cancer cells, specifically focusing on how it affected the proliferation and motility of the BGC-823 cell line. The findings showed that exposure to the extract led to a sharp drop in colony survival and significantly hindered cellular proliferation. In addition, the extract reduced the invasive behavior of the cancer cells, impaired their ability to close scratch wounds, and interfered with their ability to migr
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Written by Suhael Ahmad
Published on Issue 2 Vol 4, 2024
Radiotherapy for head and neck cancer usually involves administering a total dose ranging from 6000-7000 cGy, given daily over a 6-7 week period, and is associated with a variety of oral complications. These complications include oral mucositis, oral pain, decreased saliva secretion, an increased likelihood of dental caries, limited mouth opening, and osteoradionecrosis. This cross-sectional study aimed to assess the knowledge of Saudi dental professionals through an online survey, with 463 dent
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Written by Lauro FigueroaValverde
Published on Issue 2 Vol 4, 2024
Research indicates a growing association between breast cancer and increased mortality rates across the globe. Various risk factors, such as obesity, high-fat diets, lack of physical exercise, alcohol use, oral contraceptive consumption, genetic mutations, and others, contribute to the development of breast cancer. In addition, some studies have pointed to the role of the breast cancer gene 1 (BRCA1) in breast cancer onset. The objective of this study was to investigate how thiophene (1) and its
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Written by Wedad Hashem
Published on Issue 2 Vol 4, 2024
Despite being an uncommon hematologic malignancy in adults, acute lymphoblastic leukemia (ALL) remains a highly aggressive disease, with long-term survival rates reported between 30% and 40%. A thorough understanding of the biology of the disease is essential for the effective management of ALL, enabling the application of personalized therapeutic strategies, given the heterogeneity of patient presentations. This has further facilitated the development of targeted therapies and the integration o
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