The purpose of this research is to analyze the epidemiological trends of female-specific cancers in Malaysia. The review included studies from various sources, including the Asian Pacific Journal for Cancer Prevention, as well as databases like PubMed, Medline, Wiley Online Library, and ProQuest Central. The selected studies were published in various languages and covered all types of trials on patients of any age, between 1980 and 2016. The findings highlighted that Chinese women had the highest incidence of breast cancer, with a relative difference (RD) of 0.42 (CI = 0.41-0.43). Malay women showed a 22% higher likelihood of developing breast cancer compared to Indian women (RD = 0.22, CI = 0.21, 0.22), but 20% lower compared to Chinese women (RD = -0.20, CI = -0.21, -0.19). Cervical cancer held the second spot, with an average age-standardized rate (ASR) of 17.3. Indian women had the least risk of cervical cancer in comparison to Malays (RD = 0.22, CI = 0.18, 0.26) and Chinese women (RD = 0.46, CI = 0.41, 0.51). Ovarian cancer ranked fourth in frequency, with an ASR of 7.3. Indian women exhibited a lower risk of ovarian cancer than Chinese (RD = 0.29, CI = 0.27, 0.31) and Malay women (RD = 0.36, CI = 0.34, 0.38). By 2008, endometrial cancer ranked sixth among female cancers with an ASR of 6.5. Malay women had a slightly reduced risk of endometrial carcinoma compared to Chinese women (RD = -0.06, CI = -0.09, -0.03) but had a higher risk than Indian women (RD = 0.25, CI = 0.23, 0.28). The age group of 50-59 years saw the highest incidence for both breast and cervical cancers. Endometrial cancer was most common in women aged 60-69 years, while the risk of ovarian cancer began to rise significantly after the age of 40 years.
