Written by Gary J. Farkas
Published on Issue 1 Vol 5, 2025
This paper reviews the increased cardiovascular risks associated with spinal cord injury (SCI), focusing on the pathophysiological mechanisms, clinical manifestations, and both immediate and long-term effects. It identifies several potential risk factors for cardiovascular diseases post-SCI, including reduced physical activity, low HDL cholesterol levels, higher body fat percentage, poor glucose tolerance, insulin resistance, psychosocial influences, and emerging risk factors associated with SCI
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Written by Maria Możdżan
Published on Issue 1 Vol 5, 2025
Mitral valve prolapse (MVP), which affects approximately 2–3% of the population, is often benign but may be associated with a higher incidence of ventricular arrhythmias (VA) and sudden cardiac death (SCD). This study aimed to highlight the incidental detection of MVP among SCD cases and to investigate the associated histopathological features. In addition, we investigated the potential risk of VA in MVP patients by assessing heart rate variability (HRV) and heart rate turbulence (HRT). In 2021,
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Written by Codruta Diana Petchesi
Published on Issue 1 Vol 5, 2025
Long QT syndrome type I is an autosomal dominant disorder caused by a heterozygous loss-of-function mutation in the KCNQ1 gene, located on chromosome 11p15. This chromosomal region is subject to genomic imprinting and is also implicated in Beckwith-Wiedemann syndrome. This report describes a female patient with inherited long QT syndrome type I, present in her mother and sister, concurrently with Beckwith-Wiedemann syndrome due to hypomethylation in the imprinting control region 2 (IC2). Methyla
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Written by Olesya Olegovna Kalion
Published on Issue 1 Vol 5, 2025
Thyroid surgery is commonly indicated for a variety of clinical reasons, with one of the primary purposes being the diagnostic evaluation of thyroid tumors using fine needle biopsy. This technique continues to represent the gold standard in the evaluation of thyroid nodules. In recent years, especially over the past decade and a half, Russia has experienced a significant increase in the incidence of thyroid carcinoma. This upward trend is largely associated with the advancement and widespread im
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Written by Joanne Traeger-Synodinos
Published on Issue 1 Vol 5, 2025
The presence of alpha thalassemia and levels of hemoglobin F (HbF) significantly influence the clinical presentation of sickle cell disease (SCD) across different populations. This study was conducted to investigate the effects of these two factors on SCD patients in northern Iraq. A total of 74 patients with sickle/β0 thalassemia or sickle cell anemia, with a mean age of 16 years, participated in the study, of which 56.8% were male. Comprehensive clinical evaluations and lab tests were performe
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Written by Inês Morais
Published on Issue 1 Vol 5, 2025
Coronavirus disease (COVID-19) is caused by a novel strain of coronavirus, while malaria is a parasitic infection triggered by Plasmodium protozoans, transmitted via Anopheles mosquitoes. The simultaneous occurrence of both malaria and COVID-19, and their interplay, remains poorly documented. This study aimed to investigate the correlation between malaria and COVID-19, focusing on the disease’s severity, treatment strategies, and clinical outcomes. The research was conducted in isolation centers
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