Volume 1, Issue 1 (2021)

The present study aimed to produce an mRNA vaccine and analyze two types of vectors. According to this study, the Food and Drug Administration has fully approved the mRNA vaccine as the most effective vaccine against the 2019 coronavirus sickness. The lack of anti-vector immunity, the infrequent occurrence of insertional mutagenesis associated with it, and its therapeutic efficacy all contribute to this approval. In addition, it has an edge over traditional DNA vaccines due to its quick producti

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One's attitude towards risk is the most important measure of their ability to regulate their environment. This requires awareness of threats and decisions about proper or inappropriate responses in dangerous situations. However, numerous factors affect people's attitudes towards danger. The impact of irrational beliefs on the types of attitudes towards hazards among students with a medical and psychological-pedagogical profile was examined in this study. Participants included 438 future

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Years ago, a link was established between defective immune responses and diabetes. Notably, guidelines for diabetic patients' vaccines acquire substantial significance because of their vulnerability to infection consequences. It is interesting to note that recently there has been a greater understanding of the critical role that Saccharomyces cerevisiae (S. cerevisiae) plays as a probiotic in boosting the host immune response. Therefore, 40 rats were randomly assigned to four groups to exami

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This study was conducted to determine whether macrophage migration inhibitory factor (MIF) levels predict no-reflow in patients with ST-segment elevation myocardial infarction (STEMI). We included 120 STEMI patients who had received initial PCI therapy. Serial 12-lead ECGs acquired before and after primary PCI within 1-2 hours at 50 mm/sec were used to assess the ST-segment dynamics. When microcirculatory perfusion is compromised, the dynamics of ST-segment elevation resolution (STR) remain at 7

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This work explores the feasibility of producing alternative fuel through the pyrolysis of syringe waste (SW) and saline bottle waste (SBW). Plastic-derived medical refuse poses serious environmental and public health risks when mishandled. Laboratory runs were performed in a batch-type fixed-bed reactor, varying temperatures from 0 to 600°C at 50°C increments. The influence of temperature on product formation was examined. Key attributes of pyrolytic oil from SW and SBW—including density, kinema

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Efficiently directing patient movement within hospitals is essential for delivering effective secondary care. By treating a hospital as a set of linked compartments through which patients transition, we formulate equations that describe these flows as a network of interdependent dynamic processes. Many influences shape these interactions—some identifiable, many interacting in complex ways. Unlike discrete-event or agent-based methods, this approach does not require detailed knowledge of every un

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Choosing an appropriate biomaterial is crucial when designing scaffolds intended for biomedical use. In particular, creating nanofibrous architectures by electrospinning requires careful selection of the polymer. Poly (2-ethyl-2-oxazoline) (PEOX) is one such candidate polymer suitable for electrospinning and can be utilized to fabricate scaffolds for medical purposes. PEOX dissolves readily in water, which is a significant advantage for biological systems, and it also exhibits solubility in vari

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To explore how patients with breast cancer perceive their interactions with smart hospital applications and what they hope to see in future improvements. A descriptive qualitative approach was used. In-depth interviews were carried out with 40 breast cancer patients who had experience using smart hospital apps. The interview materials were organized and interpreted through content analysis. A total of five major themes and two supplementary themes emerged. The major themes included: favorable im

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Advances in artificial intelligence (AI)–driven medical Internet of Things (IoT) systems have greatly simplified the acquisition and sharing of clinical data. Nevertheless, issues related to confidentiality, protection of sensitive information, and communication performance have become increasingly urgent. Although numerous studies apply AI and blockchain frameworks to mitigate these concerns, limited attention has been given to how the inherently slow consensus procedures of traditional blockch

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With the emergence and spread of COVID-19 caused by SARS-CoV-2, numerous blood drives were suspended, raising concerns from late February 2020 about a potential decline in volunteer blood donors across Japan. This study aims to examine how whole blood donation, production, and inventory control of red blood cell (RBC) units at the Japanese Red Cross Society (JRCS) changed during this period. It further evaluates how the pandemic influenced blood collection activities and the delivery of RBC prod

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