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Pharmaceutical Sciences and Drug Design

Volume 1 (2021)

Enhancing Meat Paste Production: Lithium-Based Technology Optimization
Written by Miftakhutdinova Elena   Published on Vol 1, 2021
This paper aimed to create a method for turning fowl flesh that has been enhanced with lithium into a paste. The research achieved the best method for chopping minced meat for paste, which provides excellent organoleptic and physicochemical properties and low microbiological contamination. The process of rearing birds and supplementing their diet with fortified food raw materials (poultry meat) with a crucial element (lithium) has a bigger impact. The safety of using poultry paste enhanced with
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Evaluating the Clinical Efficacy of Antiviral Treatments for SARS-CoV-2
Written by Angelique Welman   Published on Vol 1, 2021
The virus that creates COVID-19, SARS-CoV-2, is highly contagious and typically replicates in the upper and lower respiratory tract to cause atypical pneumonia in humans. The gastrointestinal and cardiovascular tissues that contain its primary binding receptor, ACE2, may also be infected. A variety of therapeutic approaches have been investigated and modified to reduce the potentially dangerous clinical consequences of the COVID-19 pandemic. However, there isn't a proven cure for this illnes
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Vitamin D Deficiency and Multiple Sclerosis: Investigating a Potential Association
Written by Mustafa Mohammed Al Brahim   Published on Vol 1, 2021
Multiple sclerosis, an autoimmune demyelinating illness, is a common disease in young adults. Low vitamin D levels are a risk factor associated with multiple sclerosis. Numerous regulatory functions, particularly those related to the immune system, depend on vitamin D. Following the discovery of seasonal and geographic variations in the incidence of multiple sclerosis worldwide, it was suggested 50 years ago that vitamin D may play a role in the risk of developing and relapsing multiple sclerosi
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Quality Evaluation of Sustained-Release Domperidone Formulations
Written by Zeb-un-Nisa Zeb-un-Nisa   Published on Vol 1, 2021
Using hydrophilic Methocel® K4M, the current study sought to design a sustained-releasing and acting formulation of Domperidone, an antiemetic medication used to treat nausea and vomiting, with a typical dosage that is administered twice or three times per day. The sustained-release formulation was made using various ratios of K4M, and its quality and stability were assessed. The optimized formulation was chosen for dissolution studies and similarity profiles after pre-compression and post-compr
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In Vitro Stability Assessment of Ketoprofen Tablets Under ICHQ1A Guideline
Written by Mariana Ganea   Published on Vol 1, 2021
One of the critical components of the pharmaceutical industry is the capacity of pharmaceutical forms to remain stable over time and maintain their quality under different storage and transportation circumstances. Therefore, the amount of active components in the pharmaceutical form is evaluated following the ICHQ1A standards of the European Pharmacopoeia to ascertain the validity of the pharmaceutical product. This paper aims to investigate the stability of 100 mg ketoprofen tablets. Short-term
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Formulation and Evaluation of Immediate-Release Quetiapine Fumarate Tablets
Written by Prashant Lakshaman Pingale   Published on Vol 1, 2021
Antipsychotic medications can help manage the symptoms of schizophrenia. Several demographic and scientific elements have the potential to influence the choice of unusual neuroleptic drugs. Bipolar disorder and schizophrenia can be treated with quetiapine fumarate. When making tablets and hard-shell capsules, disintegrating agents are often utilized ingredients. The primary goal of this study was to develop a dependable immediate-release tablet formulation of the antipsychotic quetiapine. Tablet
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